National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Estradiol Cypionate

Synonyms

Estradiol Cypionate

ESTRADIOL CYPIONATE

17beta-Estradiol 17-Cyclopentylpropionate

Definitions

The cypionate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol cypionate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47991

CAS_Registry

313-06-4

Chemical_Formula

C26H36O3

code

C47991

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The cypionate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol cypionate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.

FDA_UNII_Code

7E1DV054LO

FULL_SYN

Estradiol Cypionate

ESTRADIOL CYPIONATE

17beta-Estradiol 17-Cyclopentylpropionate

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2295

label

Estradiol Cypionate

Legacy Concept Name

Estradiol_Cypionate

NSC Number

3354

Preferred_Name

Estradiol Cypionate

prefixIRI

Thesaurus:C47991

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0059610

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C478

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