National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Ropinirole Hydrochloride

Synonyms

ROPINIROLE HYDROCHLORIDE

2(H)-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, Monohydrochloride

4-(2-(Dipropylamino)ethyl)-2-indolinone Monohydrochloride

SK&F 101468-A

Ropinirole Hydrochloride

Requip

Definitions

The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47710

CAS_Registry

91374-20-8

Chemical_Formula

C16H24N2O.HCl

code

C47710

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Acting as a substitute for dopamine, ropinirole hydrochloride binds to and activates dopamine D2 and D3 receptors within the caudate putamen in the brain, thereby improving motor function.

FDA_UNII_Code

D7ZD41RZI9

FULL_SYN

ROPINIROLE HYDROCHLORIDE

2(H)-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-, Monohydrochloride

4-(2-(Dipropylamino)ethyl)-2-indolinone Monohydrochloride

SK&F 101468-A

Ropinirole Hydrochloride

Requip

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61931

label

Ropinirole Hydrochloride

Legacy Concept Name

Ropinirole_Hydrochloride

NCI_Drug_Dictionary_ID

779013

PDQ_Closed_Trial_Search_ID

779013

PDQ_Open_Trial_Search_ID

779013

Preferred_Name

Ropinirole Hydrochloride

prefixIRI

Thesaurus:C47710

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0771840

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38149

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