National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Rivastigmine Tartrate

Synonyms

Carbamic Acid, Ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl Ester,(2R,3R)-2,3-dihydroxybutanedioate(1:1)

RIVASTIGMINE TARTRATE

SDZ-ENA 713

Rivastigmine Tartrate

Exelon

Definitions

The tartrate salt form of rivastigmine, a phenylcarbamate derivative exhibiting cognitive stimulating property. Although the mechanism of action has not been fully elucidated, rivastigmine tartrate may bind reversibly to cholinesterase, thereby decreasing the breakdown of acetylcholine and enhancing cholinergic function.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47707

Accepted_Therapeutic_Use_For

Alzheimer's disease; dementia associated with Parkinson's disease

CAS_Registry

129101-54-8

CHEBI_ID

CHEBI:64358

Chemical_Formula

C14H22N2O2.C4H6O6

code

C47707

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The tartrate salt form of rivastigmine, a phenylcarbamate derivative exhibiting cognitive stimulating property. Although the mechanism of action has not been fully elucidated, rivastigmine tartrate may bind reversibly to cholinesterase, thereby decreasing the breakdown of acetylcholine and enhancing cholinergic function.

FDA_UNII_Code

9IY2357JPE

FULL_SYN

Carbamic Acid, Ethylmethyl-, 3-((1S)-1-(dimethylamino)ethyl)phenyl Ester,(2R,3R)-2,3-dihydroxybutanedioate(1:1)

RIVASTIGMINE TARTRATE

SDZ-ENA 713

Rivastigmine Tartrate

Exelon

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66519

label

Rivastigmine Tartrate

Legacy Concept Name

Rivastigmine_Tartrate

NCI_Drug_Dictionary_ID

779007

PDQ_Closed_Trial_Search_ID

779007

PDQ_Open_Trial_Search_ID

779007

Preferred_Name

Rivastigmine Tartrate

prefixIRI

Thesaurus:C47707

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0772415

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47792

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