National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Penicillin G Benzathine

Synonyms

PENICILLIN G BENZATHINE

Benzylpenicillin Benzathine Hydrate

Penicillin G Benzathine

Benzathine Benzylpenicillin Tetrahydrate

Bicillin

Permapen

Definitions

The long-acting benzathine salt form of penicillin G, a broad-spectrum penicillin antibiotic. Penicillin G benzathine binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47657

CAS_Registry

41372-02-5

Chemical_Formula

C16H20N2.2C16H18N2O4S.4H2O

code

C47657

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The long-acting benzathine salt form of penicillin G, a broad-spectrum penicillin antibiotic. Penicillin G benzathine binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall. This leads to the interruption of cell wall synthesis, consequently leading to bacterial cell growth inhibition and cell lysis.

FDA_UNII_Code

RIT82F58GK

FULL_SYN

PENICILLIN G BENZATHINE

Benzylpenicillin Benzathine Hydrate

Penicillin G Benzathine

Benzathine Benzylpenicillin Tetrahydrate

Bicillin

Permapen

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61883

label

Penicillin G Benzathine

Legacy Concept Name

Penicillin_G_Benzathine

Preferred_Name

Penicillin G Benzathine

prefixIRI

Thesaurus:C47657

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0030829

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500

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