National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Oxymorphone Hydrochloride

Synonyms

OXYMORPHONE HYDROCHLORIDE

Oxymorphone Hydrochloride

4,5-alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one Hydrochloride

Numorphan

Opana

Opana ER

Definitions

The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47648

CAS_Registry

357-07-3

Chemical_Formula

C17H19NO4.HCl

code

C47648

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of oxymorphone, a semisynthetic opioid with a potent analgesic property. Oxymorphone hydrochloride binds to and activates opiate receptors, specifically mu-receptors, in the central nervous system (CNS). This results in sedation, analgesia, decreased gastrointestinal motility, and respiratory depression.

FDA_UNII_Code

5Y2EI94NBC

FULL_SYN

OXYMORPHONE HYDROCHLORIDE

Oxymorphone Hydrochloride

4,5-alpha-Epoxy-3,14-dihydroxy-17-methylmorphinan-6-one Hydrochloride

Numorphan

Opana

Opana ER

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29314

label

Oxymorphone Hydrochloride

Legacy Concept Name

Oxymorphone_Hydrochloride

NCI_Drug_Dictionary_ID

686446

PDQ_Closed_Trial_Search_ID

686446

PDQ_Open_Trial_Search_ID

686446

Preferred_Name

Oxymorphone Hydrochloride

prefixIRI

Thesaurus:C47648

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0282275

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67413

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1506

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