Preferred Name |
Orphenadrine Citrate |
|
Synonyms |
Ethanamine, N,N-dimethyl-2-((2-methylphenyl)phenylmethoxy)-, 2-hydroxy-1,2,3-propanetricarboxylate(1:1) ORPHENADRINE CITRATE Orphenadrine Citrate Norflex |
|
Definitions |
The citrate salt form of orphenadrine with a muscle relaxant property. Although the mechanism of action has not been fully elucidated, orphenadrine citrate appears to block cholinergic receptors, thereby interfering with the transmission of nerve impulses from the spinal cord to the muscles. It does not produce myoneural block, nor does it affect crossed extensor reflexes. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47641 |
|
CAS_Registry |
4682-36-4 |
|
CHEBI_ID |
CHEBI:7790 |
|
Chemical_Formula |
C18H23NO.C6H8O7 |
|
code |
C47641 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
The citrate salt form of orphenadrine with a muscle relaxant property. Although the mechanism of action has not been fully elucidated, orphenadrine citrate appears to block cholinergic receptors, thereby interfering with the transmission of nerve impulses from the spinal cord to the muscles. It does not produce myoneural block, nor does it affect crossed extensor reflexes. |
|
FDA_UNII_Code |
X0A40N8I4S |
|
FULL_SYN |
Ethanamine, N,N-dimethyl-2-((2-methylphenyl)phenylmethoxy)-, 2-hydroxy-1,2,3-propanetricarboxylate(1:1) ORPHENADRINE CITRATE Orphenadrine Citrate Norflex |
|
Has_Free_Acid_Or_Base_Form | ||
label |
Orphenadrine Citrate |
|
Legacy Concept Name |
Orphenadrine_Citrate |
|
NCI_Drug_Dictionary_ID |
787125 |
|
PDQ_Closed_Trial_Search_ID |
787125 |
|
PDQ_Open_Trial_Search_ID |
787125 |
|
Preferred_Name |
Orphenadrine Citrate |
|
prefixIRI |
Thesaurus:C47641 |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0029310 |
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subClassOf |