loading...| Preferred Name |
Lomefloxacin Hydrochloride |
|
| Synonyms |
Lomefloxacin Hydrochloride LOMEFLOXACIN HYDROCHLORIDE (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride Maxaquin Mazaquin NY 198 |
|
| Definitions |
The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47587 |
|
| CAS_Registry |
98079-52-8 |
|
| CHEBI_ID |
CHEBI:6518 |
|
| Chemical_Formula |
C17H19F2N3O3.HCl |
|
| code |
C47587 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
|
| FDA_UNII_Code |
9VC7S3ZXXB |
|
| FULL_SYN |
Lomefloxacin Hydrochloride LOMEFLOXACIN HYDROCHLORIDE (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride Maxaquin Mazaquin NY 198 |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Lomefloxacin Hydrochloride |
|
| Legacy Concept Name |
Lomefloxacin_Hydrochloride |
|
| Preferred_Name |
Lomefloxacin Hydrochloride |
|
| prefixIRI |
Thesaurus:C47587 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0770927 |
|
| subClassOf |