National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Guanidine Hydrochloride

Synonyms

Aminoformamidine Hydrochloride

Guanidinium Chloride

GUANIDINE HYDROCHLORIDE

Guanidine Hydrochloride

Definitions

The hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes. (NCI05)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47551

CAS_Registry

50-01-1

CHEBI_ID

CHEBI:32735

Chemical_Formula

CH5N3.HCl

code

C47551

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes. (NCI05)

FDA_UNII_Code

3YQC9ZY4YB

FULL_SYN

Aminoformamidine Hydrochloride

Guanidinium Chloride

GUANIDINE HYDROCHLORIDE

Guanidine Hydrochloride

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C77851

label

Guanidine Hydrochloride

Legacy Concept Name

Guanidine_Hydrochloride

Preferred_Name

Guanidine Hydrochloride

prefixIRI

Thesaurus:C47551

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0120447

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45678

Delete Subject Author Type Created
No notes to display