loading...| Preferred Name |
Gemifloxacin Mesylate |
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| Synonyms |
Gemifloxacin Mesylate GEMIFLOXACIN MESYLATE 7-((4Z)-3-(Aminomethyl)-4-methoxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)naphthyridine-3-carboxylic Acid Monomethanesulfonate Factive |
|
| Definitions |
The mesylate salt form of gemifloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Gemifloxacin mesylate inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. This fluoroquinolone exerts an enhanced spectrum of activity against gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus, in addition to its activity against gram-negative bacteria. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47548 |
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| CAS_Registry |
204519-65-3 |
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| CHEBI_ID |
CHEBI:53749 |
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| Chemical_Formula |
C18H20FN5O4.CH4O3S |
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| code |
C47548 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
The mesylate salt form of gemifloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Gemifloxacin mesylate inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. This fluoroquinolone exerts an enhanced spectrum of activity against gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus, in addition to its activity against gram-negative bacteria. |
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| FDA_UNII_Code |
X4S9F8RL01 |
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| FULL_SYN |
Gemifloxacin Mesylate GEMIFLOXACIN MESYLATE 7-((4Z)-3-(Aminomethyl)-4-methoxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)naphthyridine-3-carboxylic Acid Monomethanesulfonate Factive |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Gemifloxacin Mesylate |
|
| Legacy Concept Name |
Gemifloxacin_Mesylate |
|
| Preferred_Name |
Gemifloxacin Mesylate |
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| prefixIRI |
Thesaurus:C47548 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C1321744 |
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| subClassOf |