National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Flurandrenolide

Synonyms

6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with Acetone

Fludroxycortide

FLURANDRENOLIDE

Flurandrenolide

Cordran

Definitions

A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47537

CAS_Registry

1524-88-5

Chemical_Formula

C24H33FO6

code

C47537

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

FDA_UNII_Code

8EUL29XUQT

FULL_SYN

6alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregn-4-ene-3,20-dione, cyclic 16,17-acetal with Acetone

Fludroxycortide

FLURANDRENOLIDE

Flurandrenolide

Cordran

label

Flurandrenolide

Legacy Concept Name

Flurandrenolide

Preferred_Name

Flurandrenolide

prefixIRI

Thesaurus:C47537

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0016374

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C521

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