loading...| Preferred Name |
Estropipate |
|
| Synonyms |
Estrone Hydrogen Sulfate compound with Piperazine(1:1) ESTROPIPATE Estropipate Piperazine, compound with 3-(Sulfooxy)estra-1,3,5(10)-trien-17-one(1:1)(9CI) Ortho-Est, Estra-1,3,5(10)-trien-17-one 3-sulphate, compound with Piperazine(1:1) Ogen Sulestrex |
|
| Definitions |
A natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47521 |
|
| CAS_Registry |
7280-37-7 |
|
| CHEBI_ID |
CHEBI:4873 |
|
| Chemical_Formula |
C18H22O5S.C4H10N2 |
|
| code |
C47521 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. |
|
| FDA_UNII_Code |
SVI38UY019 |
|
| FULL_SYN |
Estrone Hydrogen Sulfate compound with Piperazine(1:1) ESTROPIPATE Estropipate Piperazine, compound with 3-(Sulfooxy)estra-1,3,5(10)-trien-17-one(1:1)(9CI) Ortho-Est, Estra-1,3,5(10)-trien-17-one 3-sulphate, compound with Piperazine(1:1) Ogen Sulestrex |
|
| label |
Estropipate |
|
| Legacy Concept Name |
Estropipate |
|
| Preferred_Name |
Estropipate |
|
| prefixIRI |
Thesaurus:C47521 |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0071108 |
|
| subClassOf |