loading...| Preferred Name |
Ergotamine Tartrate |
|
| Synonyms |
Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-,(2R,3R)-2,3-dihydroxybutanedioate(2:1)(salt) ERGOTAMINE TARTRATE Ergotamine Tartrate Ergomar Ergostat Femergin Lingran Secupan Wigrettes |
|
| Definitions |
The tartrate salt form of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor activity. Ergotamine tartrate selectively binds to alpha-adrenergic receptors thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins. Ergotamine tartrate also blocks serotonin 5-HT1D receptors, thereby also causing vasoconstriction in cerebral blood vessels. Constriction of cerebral blood vessels caused by this agent may reduce the blood flow and pressure in cerebral arteries and may relieve the pain of vascular headaches. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47517 |
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| CAS_Registry |
24381-56-4 379-79-3 |
|
| Chemical_Formula |
2C33H35N5O5.C4H6O6 |
|
| code |
C47517 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
The tartrate salt form of ergotamine, an ergot alkaloid and adrenergic alpha agonist with vasoconstrictor activity. Ergotamine tartrate selectively binds to alpha-adrenergic receptors thereby stimulating vascular smooth muscle and causing vasoconstriction in both arteries and veins. Ergotamine tartrate also blocks serotonin 5-HT1D receptors, thereby also causing vasoconstriction in cerebral blood vessels. Constriction of cerebral blood vessels caused by this agent may reduce the blood flow and pressure in cerebral arteries and may relieve the pain of vascular headaches. |
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| FDA_UNII_Code |
MRU5XH3B48 |
|
| FULL_SYN |
Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-,(2R,3R)-2,3-dihydroxybutanedioate(2:1)(salt) ERGOTAMINE TARTRATE Ergotamine Tartrate Ergomar Ergostat Femergin Lingran Secupan Wigrettes |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Ergotamine Tartrate |
|
| Legacy Concept Name |
Ergotamine_Tartrate |
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| NSC Number |
41869 |
|
| Preferred_Name |
Ergotamine Tartrate |
|
| prefixIRI |
Thesaurus:C47517 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C2936189 |
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| subClassOf |