National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Desloratadine

Synonyms

DESLORATADINE

Desloratadine

5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-

Clarinex

Sch 34117

Definitions

A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47474

CAS_Registry

100643-71-8

CHEBI_ID

CHEBI:291342

Chemical_Formula

C19H19ClN2

code

C47474

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms.

FDA_UNII_Code

FVF865388R

FULL_SYN

DESLORATADINE

Desloratadine

5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-

Clarinex

Sch 34117

label

Desloratadine

Legacy Concept Name

Desloratadine

Preferred_Name

Desloratadine

prefixIRI

Thesaurus:C47474

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0908935

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29578

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