National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Chlortetracycline Hydrochloride

Synonyms

2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride(4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-

CHLORTETRACYCLINE HYDROCHLORIDE

7-Chlorotetracycline Hydrochloride

Chlortetracycline Hydrochloride

Aureomycin

Definitions

A tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47448

CAS_Registry

64-72-2

Chemical_Formula

C22H23ClN2O8.HCl

code

C47448

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride is bacteriostatic and inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby preventing the addition of amino acids to the growing peptide chain. This tetracycline is active against a wide range of gram-positive and gram-negative organisms, spirochetes, rickettsial species, certain protozoa and Mycoplasma and Chlamydia organisms.

FDA_UNII_Code

O1GX33ON8R

FULL_SYN

2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride(4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-

CHLORTETRACYCLINE HYDROCHLORIDE

7-Chlorotetracycline Hydrochloride

Chlortetracycline Hydrochloride

Aureomycin

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61673

label

Chlortetracycline Hydrochloride

Legacy Concept Name

Chlortetracycline_Hydrochloride

NSC Number

13252

Preferred_Name

Chlortetracycline Hydrochloride

prefixIRI

Thesaurus:C47448

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0085855

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1595

Delete Subject Author Type Created
No notes to display