Preferred Name |
Ceftizoxime Sodium |
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Synonyms |
Ceftizoxime Sodium 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2,3-dihydro-2-imino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxomonosodium Salt,(6R-(6alpha,7beta(Z)))- CEFTIZOXIME SODIUM Cefizox Epocelin |
|
Definitions |
The sodium salt form of ceftizoxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Ceftizoxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis. |
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ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47438 |
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CAS_Registry |
68401-82-1 |
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CHEBI_ID |
CHEBI:3512 |
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Chemical_Formula |
C13H12N5O5S2.Na |
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code |
C47438 |
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Concept_In_Subset | ||
Contributing_Source |
FDA |
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DEFINITION |
The sodium salt form of ceftizoxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Ceftizoxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis. |
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FDA_UNII_Code |
26337D5X88 |
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FULL_SYN |
Ceftizoxime Sodium 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((2,3-dihydro-2-imino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxomonosodium Salt,(6R-(6alpha,7beta(Z)))- CEFTIZOXIME SODIUM Cefizox Epocelin |
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Has_Free_Acid_Or_Base_Form | ||
label |
Ceftizoxime Sodium |
|
Legacy Concept Name |
Ceftizoxime_Sodium |
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Preferred_Name |
Ceftizoxime Sodium |
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prefixIRI |
Thesaurus:C47438 |
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Semantic_Type |
Pharmacologic Substance |
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UMLS_CUI |
C0282391 |
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subClassOf |