National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Safrole

Synonyms

5-(2-Propenyl)-1,3-benzodioxole

Allylcatechol Methylene Ether

1-Allyl-3,4-methylenedioxybenzene

SAFROLE

Safrole

Definitions

A naturally-occurring, colorless to slightly yellow liquid that is soluble in ethanol, ether, and chloroform. Safrole is no longer used in the United States. Minimal exposure to safrole may occur through the use of edible spices, including nutmeg and mace, which contain low levels of this compound. It is reasonably anticipated to be a human carcinogen. (NCI05)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C44443

CAS_Registry

94-59-7

code

C44443

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A naturally-occurring, colorless to slightly yellow liquid that is soluble in ethanol, ether, and chloroform. Safrole is no longer used in the United States. Minimal exposure to safrole may occur through the use of edible spices, including nutmeg and mace, which contain low levels of this compound. It is reasonably anticipated to be a human carcinogen. (NCI05)

FDA_UNII_Code

RSB34337V9

FULL_SYN

5-(2-Propenyl)-1,3-benzodioxole

Allylcatechol Methylene Ether

1-Allyl-3,4-methylenedioxybenzene

SAFROLE

Safrole

label

Safrole

Legacy Concept Name

Safrole

NSC Number

11831

Preferred_Name

Safrole

prefixIRI

Thesaurus:C44443

Semantic_Type

Hazardous or Poisonous Substance

UMLS_CUI

C0036049

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C45187

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