loading...| Preferred Name |
Contact Hypersensitivity |
|
| Synonyms |
Contact Hypersensitivity |
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| Definitions |
Contact hypersensitivity is an inflammatory response induced by antigen-reactive T cells that are exposed to antigen on the skin surface (epidermis). Poison ivy is a frequent cause of such reactivity, due to the urushiol from the plant, as are a variety of antigens derived from industrial exposure (e.g. rubber, chromate, nickel). These antigens induce the appearance of Th1-like T cells, which presumably produce IFN to activate macrophages. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3668 |
|
| code |
C3668 |
|
| DEFINITION |
Contact hypersensitivity is an inflammatory response induced by antigen-reactive T cells that are exposed to antigen on the skin surface (epidermis). Poison ivy is a frequent cause of such reactivity, due to the urushiol from the plant, as are a variety of antigens derived from industrial exposure (e.g. rubber, chromate, nickel). These antigens induce the appearance of Th1-like T cells, which presumably produce IFN to activate macrophages. |
|
| FULL_SYN |
Contact Hypersensitivity |
|
| label |
Contact Hypersensitivity |
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| Legacy Concept Name |
Contact_Hypersensitivity |
|
| Preferred_Name |
Contact Hypersensitivity |
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| prefixIRI |
Thesaurus:C3668 |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0162351 |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/SNOMEDCT/29268000 | SNOMEDCT | LOOM | |
| http://purl.obolibrary.org/obo/NCIT_C3668 | BERO | LOOM | |
| http://purl.bioontology.org/ontology/SNMI/F-C3340 | SNMI | LOOM |