loading...| Preferred Name |
Beclomethasone Dipropionate |
|
| Synonyms |
(11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione Dipropionate Beclomethasone Dipropionate BECLOMETHASONE DIPROPIONATE Beclovent Beconase QNASL Qvar SCH-18020W Vancenase Vanceril |
|
| Definitions |
The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C299 |
|
| Accepted_Therapeutic_Use_For |
Asthma; GI graft vs. host disease, prevention; Nasal polyps; Rhinitis |
|
| CAS_Registry |
5534-09-8 |
|
| CHEBI_ID |
CHEBI:3002 |
|
| Chemical_Formula |
C28H37ClO7 |
|
| code |
C299 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA HL7 |
|
| DEFINITION |
The dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. |
|
| Display_Name |
Beclomethasone Dipropionate |
|
| FDA_UNII_Code |
5B307S63B2 |
|
| FULL_SYN |
(11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione Dipropionate Beclomethasone Dipropionate BECLOMETHASONE DIPROPIONATE Beclovent Beconase QNASL Qvar SCH-18020W Vancenase Vanceril |
|
| Has_Target | ||
| label |
Beclomethasone Dipropionate |
|
| Legacy Concept Name |
Beclomethasone |
|
| NCI_Drug_Dictionary_ID |
39272 |
|
| PDQ_Closed_Trial_Search_ID |
39272 |
|
| PDQ_Open_Trial_Search_ID |
39272 |
|
| Preferred_Name |
Beclomethasone Dipropionate |
|
| prefixIRI |
Thesaurus:C299 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0004906 |
|
| subClassOf |