loading...| Preferred Name |
Tamsulosin Hydrochloride |
|
| Synonyms |
Tamsulosin Hydrochloride TAMSULOSIN HYDROCHLORIDE tamsulosin hydrochloride Flomax |
|
| Definitions |
The hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29486 |
|
| Accepted_Therapeutic_Use_For |
Benign Prostatic Hyperplasia |
|
| ALT_DEFINITION |
A drug used to treat urinary problems caused by an enlarged prostate. Flomax relaxes the muscles of the prostate and bladder, which helps the flow of urine. It is a type of alpha blocker. |
|
| CAS_Registry |
106463-17-6 |
|
| CHEBI_ID |
CHEBI:9399 |
|
| Chemical_Formula |
C20H28N2O5S.HCl |
|
| code |
C29486 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The hydrochloride salt of tamsulosin, a sulfonamide derivative with adrenergic antagonist activity. Tamsulosin selectivity binds to and blocks the activity of alpha1 adrenoreceptors in the human prostate and bladder neck; blockade of these adrenoceptors can cause smooth muscle in the prostate and bladder neck to relax, resulting in an improvement in urinary flow rate. |
|
| FDA_UNII_Code |
11SV1951MR |
|
| FULL_SYN |
Tamsulosin Hydrochloride TAMSULOSIN HYDROCHLORIDE tamsulosin hydrochloride Flomax |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Tamsulosin Hydrochloride |
|
| Legacy Concept Name |
Tamsulosin_Hydrochloride |
|
| NCI_Drug_Dictionary_ID |
479148 |
|
| PDQ_Closed_Trial_Search_ID |
479148 |
|
| PDQ_Open_Trial_Search_ID |
479148 |
|
| Preferred_Name |
Tamsulosin Hydrochloride |
|
| prefixIRI |
Thesaurus:C29486 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0771774 |
|
| subClassOf |