National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Pseudoephedrine Hydrochloride

Synonyms

Pseudoephedrine.HCl

Pseudoephedrine Hydrochloride

PSEUDOEPHEDRINE HYDROCHLORIDE

Definitions

The hydrochloride salt form of pseudoephedrine, a phenethylamine and an diastereomer of ephedrine with sympathomimetic property. Pseudoephedrine hydrochloride displaces norepinephrine from storage vesicles in presynaptic neurones, thereby releasing norepinephrine into the neuronal synapses where it stimulates primarily alpha-adrenergic receptors. It also has weak direct agonist activity at alpha- and beta- adrenergic receptors. Receptor stimulation results in vasoconstriction and decreases nasal and sinus congestion.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29390

CAS_Registry

345-78-8

CHEBI_ID

CHEBI:8604

Chemical_Formula

C10H15NO.HCl

code

C29390

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of pseudoephedrine, a phenethylamine and an diastereomer of ephedrine with sympathomimetic property. Pseudoephedrine hydrochloride displaces norepinephrine from storage vesicles in presynaptic neurones, thereby releasing norepinephrine into the neuronal synapses where it stimulates primarily alpha-adrenergic receptors. It also has weak direct agonist activity at alpha- and beta- adrenergic receptors. Receptor stimulation results in vasoconstriction and decreases nasal and sinus congestion.

FDA_UNII_Code

6V9V2RYJ8N

FULL_SYN

Pseudoephedrine.HCl

Pseudoephedrine Hydrochloride

PSEUDOEPHEDRINE HYDROCHLORIDE

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61914

label

Pseudoephedrine Hydrochloride

Legacy Concept Name

Pseudoephedrine_Hydrochloride

NSC Number

106567

33634

Preferred_Name

Pseudoephedrine Hydrochloride

prefixIRI

Thesaurus:C29390

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0304430

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29709

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