National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Pramipexole Dihydrochloride

Synonyms

Pramipexole Dihydrochloride

PRAMIPEXOLE DIHYDROCHLORIDE

Mirapex

Definitions

The hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and substantia nigra of the brain. Compared to other dopamine agonists, the use of this agent may be associated with fewer dyskinetic side effects in treated subjects. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29374

CAS_Registry

191217-81-9

CHEBI_ID

CHEBI:51147

Chemical_Formula

C10H17N3S.2HCl.H2O

code

C29374

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and substantia nigra of the brain. Compared to other dopamine agonists, the use of this agent may be associated with fewer dyskinetic side effects in treated subjects. (NCI04)

FDA_UNII_Code

3D867NP06J

FULL_SYN

Pramipexole Dihydrochloride

PRAMIPEXOLE DIHYDROCHLORIDE

Mirapex

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66456

label

Pramipexole Dihydrochloride

Legacy Concept Name

Pramipexole_Dihydrochloride

NCI_Drug_Dictionary_ID

779012

PDQ_Closed_Trial_Search_ID

779012

PDQ_Open_Trial_Search_ID

779012

Preferred_Name

Pramipexole Dihydrochloride

prefixIRI

Thesaurus:C29374

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0772054

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C38149

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66884

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