National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Oxymetazoline Hydrochloride

Synonyms

Oxymetazoline Hydrochloride

Visine L.R.

OXYMETAZOLINE HYDROCHLORIDE

Afrin

Ocuclear

Definitions

The hydrochloride salt form of oxymetazoline, an imidazole derivative with a direct acting sympathomimetic property. Oxymetazoline binds to and activates alpha-2 adrenergic receptors. Upon nasal or ocular administration, oxymetazoline constricts the arterioles in the nose and eye, resulting in decreased nasal and conjunctival congestion, respectively.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29313

CAS_Registry

2315-02-8

Chemical_Formula

C16H24N2O.HCl

code

C29313

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The hydrochloride salt form of oxymetazoline, an imidazole derivative with a direct acting sympathomimetic property. Oxymetazoline binds to and activates alpha-2 adrenergic receptors. Upon nasal or ocular administration, oxymetazoline constricts the arterioles in the nose and eye, resulting in decreased nasal and conjunctival congestion, respectively.

FDA_UNII_Code

K89MJ0S5VY

FULL_SYN

Oxymetazoline Hydrochloride

Visine L.R.

OXYMETAZOLINE HYDROCHLORIDE

Afrin

Ocuclear

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61871

label

Oxymetazoline Hydrochloride

Legacy Concept Name

Oxymetazoline_Hydrochloride

Preferred_Name

Oxymetazoline Hydrochloride

prefixIRI

Thesaurus:C29313

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0357797

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29709

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