loading...| Preferred Name |
Imipramine Hydrochloride |
|
| Synonyms |
IMIPRAMINE HYDROCHLORIDE Imipramine Hydrochloride Tofranil |
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| Definitions |
The hydrochloride salt form of imipramine, a synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29116 |
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| CAS_Registry |
113-52-0 |
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| CHEBI_ID |
CHEBI:5882 |
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| Chemical_Formula |
C19H24N2.HCl |
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| code |
C29116 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA |
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| DEFINITION |
The hydrochloride salt form of imipramine, a synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04) |
|
| Display_Name |
Imipramine Hydrochloride |
|
| FDA_UNII_Code |
BKE5Q1J60U |
|
| FULL_SYN |
IMIPRAMINE HYDROCHLORIDE Imipramine Hydrochloride Tofranil |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Imipramine Hydrochloride |
|
| Legacy Concept Name |
Imipramine |
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| NSC Number |
114900 |
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| Preferred_Name |
Imipramine Hydrochloride |
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| prefixIRI |
Thesaurus:C29116 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0589978 |
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| subClassOf |