loading...| Preferred Name |
Hydroxychloroquine Sulfate |
|
| Synonyms |
Hydroxychloroquine Sulfate HYDROXYCHLOROQUINE SULFATE Plaquenil |
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| Definitions |
A synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites (Plasmodium vivax, ovale, and malariae) by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Hydroxychloroquine also has anti-inflammatory properties and is used in the treatment of rheumatoid arthritis and lupus erythematosus. (NCI04) |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29101 |
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| CAS_Registry |
747-36-4 |
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| Chemical_Formula |
C18H26ClN3O.H2SO4 |
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| code |
C29101 |
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| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA |
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| DEFINITION |
A synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites (Plasmodium vivax, ovale, and malariae) by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Hydroxychloroquine also has anti-inflammatory properties and is used in the treatment of rheumatoid arthritis and lupus erythematosus. (NCI04) |
|
| Display_Name |
Hydroxychloroquine Sulfate |
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| FDA_UNII_Code |
8Q2869CNVH |
|
| FULL_SYN |
Hydroxychloroquine Sulfate HYDROXYCHLOROQUINE SULFATE Plaquenil |
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| Has_Free_Acid_Or_Base_Form | ||
| label |
Hydroxychloroquine Sulfate |
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| Legacy Concept Name |
Hydroxychloroquine_Sulfate |
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| NCI_Drug_Dictionary_ID |
801639 |
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| NSC Number |
4375 |
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| PDQ_Closed_Trial_Search_ID |
801639 |
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| PDQ_Open_Trial_Search_ID |
801639 |
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| Preferred_Name |
Hydroxychloroquine Sulfate |
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| prefixIRI |
Thesaurus:C29101 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0596007 |
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| subClassOf |