loading...| Preferred Name |
Hydrocodone Bitartrate |
|
| Synonyms |
Hydrocodone Bitartrate HYDROCODONE BITARTRATE hydrocodone bitartrate Hycodan |
|
| Definitions |
The bitartrate salt form of hydrocodone, a semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29099 |
|
| ALT_DEFINITION |
A drug used to treat moderate to severe pain and cough. Hydrocodone bitartrate is made from codeine and binds to opioid receptors in the central nervous system. It is a type of analgesic agent, a type of antitussive, and a type of opiate. |
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| CAS_Registry |
34195-34-1 |
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| CHEBI_ID |
CHEBI:5780 |
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| Chemical_Formula |
2C18H21NO3.2C4H6O6.5H2O |
|
| code |
C29099 |
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| Concept_In_Subset | ||
| Contributing_Source |
FDA |
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| DEFINITION |
The bitartrate salt form of hydrocodone, a semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and activates the mu-opioid receptor in the central nervous system (CNS). This leads to analgesia, euphoria, respiratory depression, miosis, decreased gastrointestinal motility, cough suppression and physical dependence. Hydrocodone is converted to hydromorphone by the cytochrome P450 enzyme CYP2D6. |
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| FDA_UNII_Code |
NO70W886KK |
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| FULL_SYN |
Hydrocodone Bitartrate HYDROCODONE BITARTRATE hydrocodone bitartrate Hycodan |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Hydrocodone Bitartrate |
|
| Legacy Concept Name |
Hydrocodone |
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| NSC Number |
19044 |
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| Preferred_Name |
Hydrocodone Bitartrate |
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| prefixIRI |
Thesaurus:C29099 |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0546868 |
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| subClassOf |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67413 |