loading...| Preferred Name |
Glycopyrrolate |
|
| Synonyms |
Glycopyrrolate Glycopyrronium Bromide GLYCOPYRROLATE Robinul Forte Pyrrolidinium, 3-((Cyclopentylhydroxyphenylacetyl)oxy)-1,1-dimethyl-, Bromide Robinul |
|
| Definitions |
A synthetic quaternary ammonium that is an anticholinergic agent with antispasmodic activity. Glycopyrrolate competitively binds to peripheral muscarinic receptors in the autonomic effector cells of, and inhibits cholinergic transmission in smooth muscle, cardiac muscle, the sinoatrial (SA) node, the atrioventricular (AV) node, exocrine glands and in the autonomic ganglia. Blockage of cholinergic transmission, in smooth muscle cells located in the gastrointestinal tract and the bladder, causes smooth muscle relaxation and prevents the occurrence of painful spasms. In addition, glycopyrrolate inhibits the release of gastric, pharyngeal, tracheal, and bronchial secretions. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29078 |
|
| CAS_Registry |
51186-83-5 |
|
| Chemical_Formula |
C19H28NO3.Br |
|
| code |
C29078 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
A synthetic quaternary ammonium that is an anticholinergic agent with antispasmodic activity. Glycopyrrolate competitively binds to peripheral muscarinic receptors in the autonomic effector cells of, and inhibits cholinergic transmission in smooth muscle, cardiac muscle, the sinoatrial (SA) node, the atrioventricular (AV) node, exocrine glands and in the autonomic ganglia. Blockage of cholinergic transmission, in smooth muscle cells located in the gastrointestinal tract and the bladder, causes smooth muscle relaxation and prevents the occurrence of painful spasms. In addition, glycopyrrolate inhibits the release of gastric, pharyngeal, tracheal, and bronchial secretions. |
|
| FDA_UNII_Code |
V92SO9WP2I |
|
| FULL_SYN |
Glycopyrrolate Glycopyrronium Bromide GLYCOPYRROLATE Robinul Forte Pyrrolidinium, 3-((Cyclopentylhydroxyphenylacetyl)oxy)-1,1-dimethyl-, Bromide Robinul |
|
| label |
Glycopyrrolate |
|
| Legacy Concept Name |
Glycopyrrolate |
|
| NCI_Drug_Dictionary_ID |
764369 |
|
| NSC Number |
250836 251251 251252 |
|
| PDQ_Closed_Trial_Search_ID |
764369 |
|
| PDQ_Open_Trial_Search_ID |
764369 |
|
| Preferred_Name |
Glycopyrrolate |
|
| prefixIRI |
Thesaurus:C29078 |
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| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0017970 |
|
| subClassOf |