National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Emetine Hydrochloride

Synonyms

Emetine Hydrochloride

EMETINE HYDROCHLORIDE

Definitions

The chloride salt of a white crystalline bitter alkaloid isolated from the root of the plant Psychotria Ipecacuanha (ipecac root) and other plants with antiemetic and anthelminthic properties. Emetine inhibits protein synthesis in eukaryotic (but not prokaryotic) cells by irreversibly blocking ribosome movement along the mRNA strand and inhibits DNA replication in the early S phase of the cell cycle. (NCI04)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29018

CAS_Registry

316-42-7

Chemical_Formula

C29H40N2O4.2HCl

code

C29018

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The chloride salt of a white crystalline bitter alkaloid isolated from the root of the plant Psychotria Ipecacuanha (ipecac root) and other plants with antiemetic and anthelminthic properties. Emetine inhibits protein synthesis in eukaryotic (but not prokaryotic) cells by irreversibly blocking ribosome movement along the mRNA strand and inhibits DNA replication in the early S phase of the cell cycle. (NCI04)

FDA_UNII_Code

U52OG12P96

FULL_SYN

Emetine Hydrochloride

EMETINE HYDROCHLORIDE

Has_Free_Acid_Or_Base_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C81578

label

Emetine Hydrochloride

Legacy Concept Name

Emetine_Hydrochloride

Preferred_Name

Emetine Hydrochloride

prefixIRI

Thesaurus:C29018

Semantic_Type

Organic Chemical

Pharmacologic Substance

UMLS_CUI

C0887359

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C784

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