loading...| Preferred Name |
Citalopram Hydrobromide |
|
| Synonyms |
CITALOPRAM HYDROBROMIDE 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile Monohydrobromide Lu 10-171-B Citalopram Hydrobromide Celexa Elopram Seropram citalopram |
|
| Definitions |
The orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), citalopram selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA). |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28932 |
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| ALT_DEFINITION |
A drug used to treat depression. It belongs to the families of drugs called antidepressant agents and selective serotonin reuptake inhibitors (SSRIs). |
|
| CAS_Registry |
59729-32-7 |
|
| CHEBI_ID |
CHEBI:3724 |
|
| Chemical_Formula |
C20H21FN2O.BrH |
|
| code |
C28932 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
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| Contributing_Source |
CTRP FDA |
|
| DEFINITION |
The orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. As a selective serotonin reuptake inhibitor (SSRI), citalopram selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). This agent has minimal effects on the CNS neuronal reuptake of norepinephrine (NE) and dopamine (DA). |
|
| Display_Name |
Citalopram Hydrobromide |
|
| FDA_UNII_Code |
I1E9D14F36 |
|
| FULL_SYN |
CITALOPRAM HYDROBROMIDE 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile Monohydrobromide Lu 10-171-B Citalopram Hydrobromide Celexa Elopram Seropram citalopram |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Citalopram Hydrobromide |
|
| Legacy Concept Name |
Citalopram_Hydrobromide |
|
| NCI_Drug_Dictionary_ID |
500063 |
|
| PDQ_Closed_Trial_Search_ID |
500063 |
|
| PDQ_Open_Trial_Search_ID |
500063 |
|
| Preferred_Name |
Citalopram Hydrobromide |
|
| prefixIRI |
Thesaurus:C28932 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0724555 |
|
| subClassOf |