loading...| Preferred Name |
Bacitracin Zinc |
|
| Synonyms |
Bacitracin Zinc BACITRACIN ZINC Ziba-Rx |
|
| Definitions |
The zinc salt form of bacitracin, a complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin zinc binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall, thereby interfering with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and preventing peptidoglycan synthesis which leads to cell lysis. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C28857 |
|
| CAS_Registry |
1405-89-6 |
|
| code |
C28857 |
|
| Concept_In_Subset | ||
| Contributing_Source |
FDA |
|
| DEFINITION |
The zinc salt form of bacitracin, a complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin zinc binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall, thereby interfering with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and preventing peptidoglycan synthesis which leads to cell lysis. |
|
| FDA_UNII_Code |
89Y4M234ES |
|
| FULL_SYN |
Bacitracin Zinc BACITRACIN ZINC Ziba-Rx |
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Bacitracin Zinc |
|
| Legacy Concept Name |
Bacitracin_Zinc |
|
| Preferred_Name |
Bacitracin Zinc |
|
| prefixIRI |
Thesaurus:C28857 |
|
| Semantic_Type |
Pharmacologic Substance Antibiotic |
|
| UMLS_CUI |
C0043483 |
|
| subClassOf |