National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Dexmethylphenidate

Synonyms

Dexmethylphenidate

dexmethylphenidate

DEXMETHYLPHENIDATE

Definitions

The d-threo-enantiomer of methylphenidate, a central nervous system stimulant, appearing to block the reuptake of norepinephrine and dopamine into the presynaptic neuron, increasing their availability in the extracellular space. The mechanism of action in Attention Deficit Hyperactivity Disorder is unknown. (NCI)

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C26642

Accepted_Therapeutic_Use_For

Attention Deficit Hyperactivity Disorder.

ALT_DEFINITION

A substance being studied in the treatment of fatigue and nervous system side effects caused by chemotherapy. It is a type of central nervous system stimulant.

CAS_Registry

40431-64-9

Chemical_Formula

C14H19NO2

code

C26642

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

The d-threo-enantiomer of methylphenidate, a central nervous system stimulant, appearing to block the reuptake of norepinephrine and dopamine into the presynaptic neuron, increasing their availability in the extracellular space. The mechanism of action in Attention Deficit Hyperactivity Disorder is unknown. (NCI)

FDA_UNII_Code

M32RH9MFGP

FULL_SYN

Dexmethylphenidate

dexmethylphenidate

DEXMETHYLPHENIDATE

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47480

label

Dexmethylphenidate

Legacy Concept Name

Dexmethylphenidate

NCI_Drug_Dictionary_ID

269067

PDQ_Closed_Trial_Search_ID

269067

PDQ_Open_Trial_Search_ID

269067

Preferred_Name

Dexmethylphenidate

prefixIRI

Thesaurus:C26642

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C1169997

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47795

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_51860 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 OBA LOOM
http://www.case.edu/EpilepsyOntology.owl#Dexmethylphenidate EPSO LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 CHEBI LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C1169997 OCHV LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_51860 NIFSTD LOOM
http://purl.bioontology.org/ontology/ATC/N06BA11 ATC LOOM
http://purl.obolibrary.org/obo/dinto_DB06701 DINTO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000269067 PDQ LOOM
http://purl.bioontology.org/ontology/VANDF/4021285 VANDF LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#55545 OCHV LOOM
https://go.drugbank.com/drugs/DB06701 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.241.223.601.600.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.621.460.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/767715008 SNOMEDCT LOOM
http://www.drugbank.ca/drugs/DB06701 FTC LOOM
http://purl.jp/bio/4/id/201306054154781813 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148722 NDFRT LOOM
http://www.case.edu/EpSO.owl#Dexmethylphenidate MEPO LOOM
http://purl.bioontology.org/ontology/RXNORM/352372 RXNORM LOOM
http://purl.obolibrary.org/obo/NCIT_C26642 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D064699 RH-MESH LOOM