National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Low Molecular Weight Heparin

Synonyms

Low Molecular Weight Heparin

Low-molecular-weight heparin

LMWH

Definitions

Substances comprised of fragmented heparin molecules derived from unfractionated heparin that bind to antithrombin III with a molecular weight ranging from 1000 to 10,000 daltons, which causes changes in property from unfractionated heparin, including decreased protein binding, enhanced bioavailability, decreased platelet interaction, and decreased binding to thrombin.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2578

ALT_DEFINITION

Low-molecular-weight heparin compounds are fractions of heparin that primarily act by inhibiting the activated clotting factor X. Examples include enoxaparin and dalteparin.

code

C2578

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191406

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191200

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191387

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C191671

Contributing_Source

ACC/AHA

CTRP

DEFINITION

Substances comprised of fragmented heparin molecules derived from unfractionated heparin that bind to antithrombin III with a molecular weight ranging from 1000 to 10,000 daltons, which causes changes in property from unfractionated heparin, including decreased protein binding, enhanced bioavailability, decreased platelet interaction, and decreased binding to thrombin.

Display_Name

Low Molecular Weight Heparin

FULL_SYN

Low Molecular Weight Heparin

Low-molecular-weight heparin

LMWH

label

Low Molecular Weight Heparin

Legacy Concept Name

Low_Molecular_Weight_Heparin

Preferred_Name

Low Molecular Weight Heparin

prefixIRI

Thesaurus:C2578

Semantic_Type

Classification

UMLS_CUI

C0019139

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C263

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