National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Thyroglobulin

Synonyms

Thyroglobulin

thyroglobulin

THYROGLOBULIN

Thyroid Thyroglobulin

TG

Tg

Definitions

Thyroglobulin (2768 aa, ~305 kDa) is encoded by the human TG gene. This protein is involved in thyroid hormone synthesis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2304

ALT_DEFINITION

The form that thyroid hormone takes when stored in the cells of the thyroid. If the thyroid has been removed, thyroglobulin should not show up on a blood test. Doctors measure thyroglobulin level in blood to detect thyroid cancer cells that remain in the body after treatment.

An antigen encoded by the TG gene that regulates thyroid hormone synthesis. It can be considered as an autoantigen and is commonly associated with autoimmune thyroid diseases.

code

C2304

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C118168

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C181169

Contributing_Source

CDISC

CTRP

DEFINITION

Thyroglobulin (2768 aa, ~305 kDa) is encoded by the human TG gene. This protein is involved in thyroid hormone synthesis.

DesignNote

Thyroglobulin is the precursor for both the free and iodinated forms of thyroxine (T4) and triiodothyronine (T3).

Display_Name

Thyroglobulin

FULL_SYN

Thyroglobulin

thyroglobulin

THYROGLOBULIN

Thyroid Thyroglobulin

TG

Tg

label

Thyroglobulin

Legacy Concept Name

Thyroglobulin

OMIM_Number

188450

Preferred_Name

Thyroglobulin

prefixIRI

Thesaurus:C2304

Semantic_Type

Amino Acid, Peptide, or Protein

Hormone

Swiss_Prot

P01266

UMLS_CUI

C0040123

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1746

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http://purl.obolibrary.org/obo/PR_000016283 EFO LOOM
http://purl.obolibrary.org/obo/PR_000016283 UBERON LOOM
http://purl.bioontology.org/ontology/LNC/LP14697-4 LOINC LOOM
http://purl.obolibrary.org/obo/dinto_DB01584 DINTO LOOM
http://purl.obolibrary.org/obo/DRON_00011660 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00011660 DRON LOOM
http://purl.bioontology.org/ontology/RXNORM/10565 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D013954 RH-MESH LOOM
http://www.orpha.net/ORDO/Orphanet_168347 ORDO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/23959001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005047 LOINC LOOM
http://localhost/plosthes.2017-1#6114 PLOSTHES LOOM
http://purl.bioontology.org/ontology/RCD/X80QQ RCD LOOM
https://go.drugbank.com/drugs/DB01584 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.486.706 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Thyroglobulin GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0040123 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147158 NDFRT LOOM
http://purl.jp/bio/4/id/200906012177861159 IOBC LOOM
http://purl.bioontology.org/ontology/MEDDRA/10061136 MEDDRA LOOM
http://www.ncbi.nlm.nih.gov/gene/21819 NIFSTD LOOM
http://purl.bioontology.org/ontology/CSP/2929-0500 CRISP LOOM
http://doe-generated-ontology.com/OntoAD#C0040123 ONTOAD LOOM
http://id.nlm.nih.gov/mesh/D013954 MDM LOOM
http://purl.bioontology.org/ontology/OMIM/188450 OMIM LOOM
http://purl.bioontology.org/ontology/MESH/D013954 MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00022866 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12254 OCHV LOOM
http://purl.obolibrary.org/obo/MESH_D013954 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.377.856 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/F-B3130 SNMI LOOM
http://www.semanticweb.org/hx-jta/ontologies/thyroid_cancer_ontology#Thyroglobulin TCO LOOM
http://purl.bioontology.org/ontology/VANDF/4018856 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.395.768 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0014799 OMIT LOOM
http://purl.bioontology.org/ontology/CPT/84432 CPT LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039300 PDQ LOOM
http://purl.obolibrary.org/obo/PR_000016283 PR LOOM
http://purl.obolibrary.org/obo/PR_000016283 NIFSTD LOOM
http://www.limics.org/hrdo/rdfns#gen_id_17751 HRDO LOOM
http://purl.obolibrary.org/obo/NCIT_C2304 BERO LOOM