loading...| Preferred Name |
DNA Mismatch Repair Protein Mlh1 |
|
| Synonyms |
MLH1 Protein MutL Protein Homolog 1 DNA Mismatch Repair Protein Mlh1 MUTL Protein Homolog 1 Mismatch DNA Repair Protein MLH1 MLH1 Gene Product Mismatch Repair Protein MLH1 hMLH1 Protein DNA Mismatch Repair Protein MLH1 COCA2 FCC2 HNPCC HNPCC2 MGC5172 MLH1 |
|
| Definitions |
DNA mismatch repair protein Mlh1 (756 aa, ~85 kDa) is encoded by the human MLH1 gene. This protein is involved in post-replicative DNA mismatch repair. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C21464 |
|
| code |
C21464 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C156952 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142800 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 |
|
| Contributing_Source |
CPTAC CTRP |
|
| DEFINITION |
DNA mismatch repair protein Mlh1 (756 aa, ~85 kDa) is encoded by the human MLH1 gene. This protein is involved in post-replicative DNA mismatch repair. |
|
| DesignNote |
MLH1 is part of the multi-subunit BASC repair complex containing ATM, BLM, MSH2, MSH6, BRCA1, the RAD50/MRE11/NBS1 complex, and the RFC1/RFC2/RFC4 complex. MLH1 is homologous to MutL, which hydrolyzes ATP. (from OMIM 120436) |
|
| Display_Name |
DNA Mismatch Repair Protein Mlh1 |
|
| FULL_SYN |
MLH1 Protein MutL Protein Homolog 1 DNA Mismatch Repair Protein Mlh1 MUTL Protein Homolog 1 Mismatch DNA Repair Protein MLH1 MLH1 Gene Product Mismatch Repair Protein MLH1 hMLH1 Protein DNA Mismatch Repair Protein MLH1 COCA2 FCC2 HNPCC HNPCC2 MGC5172 MLH1 |
|
| label |
DNA Mismatch Repair Protein Mlh1 |
|
| Legacy Concept Name |
DNA_Mismatch_Repair_Protein-MLH1 |
|
| OMIM_Number |
120436 |
|
| Preferred_Name |
DNA Mismatch Repair Protein Mlh1 |
|
| prefixIRI |
Thesaurus:C21464 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein |
|
| Swiss_Prot |
P40692 |
|
| UMLS_CUI |
C0252642 |
|
| subClassOf |