Preferred Name |
Thrombopoietin |
|
Synonyms |
Megakaryocyte Colony-Stimulating Factor Megakaryocyte Stimulating Factor C-MPL Ligand Megakaryocyte Growth and Development Factor Megakaryocyte Colony Stimulating Factor Thrombopoietin thrombopoietin Prepro-Thrombopoietin Myeloproliferative Leukemia Virus Oncogene Ligand MGDF ML MPL Ligand THPO TPO TSF |
|
Definitions |
Thrombopoietin (353 aa, ~38 kDa) is encoded by the human THPO gene. This protein is involved in both megakaryocyte differentiation and platelet activation. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20441 |
|
ALT_DEFINITION |
A substance made by the body that helps make blood cells, especially platelets. A form of TPO made in the laboratory is called recombinant human TPO and rHu TPO. TPO is being studied as a way to increase the number of platelets in cancer patients receiving chemotherapy. |
|
code |
C20441 |
|
Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
Contributing_Source |
CTRP |
|
DEFINITION |
Thrombopoietin (353 aa, ~38 kDa) is encoded by the human THPO gene. This protein is involved in both megakaryocyte differentiation and platelet activation. |
|
Display_Name |
Thrombopoietin |
|
FULL_SYN |
Megakaryocyte Colony-Stimulating Factor Megakaryocyte Stimulating Factor C-MPL Ligand Megakaryocyte Growth and Development Factor Megakaryocyte Colony Stimulating Factor Thrombopoietin thrombopoietin Prepro-Thrombopoietin Myeloproliferative Leukemia Virus Oncogene Ligand MGDF ML MPL Ligand THPO TPO TSF |
|
label |
Thrombopoietin |
|
Legacy Concept Name |
Thrombopoietin |
|
OMIM_Number |
600044 |
|
Preferred_Name |
Thrombopoietin |
|
prefixIRI |
Thesaurus:C20441 |
|
Semantic_Type |
Amino Acid, Peptide, or Protein Hormone |
|
Swiss_Prot |
P40225 |
|
UMLS_CUI |
C0040052 |
|
subClassOf |