loading...| Preferred Name |
Toremifene Citrate |
|
| Synonyms |
2-(p-[(Z)-4-chloro-1,2-diphenyl-1-butenyl]-phenoxy)- N,N-dimethylethylamine citrate (1:1) (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate (1:1) Toremifene citrate Toremifene Citrate TOREMIFENE CITRATE Acapodene FC-1157a Fareston GTx-006 |
|
| Definitions |
The citrate salt of a nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which is manifested depending on the tissue or species. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1756 |
|
| CAS_Registry |
89778-27-8 |
|
| Chemical_Formula |
C26H28ClNO.C6H8O7 |
|
| code |
C1756 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
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| Contributing_Source |
CTRP FDA GDC |
|
| DEFINITION |
The citrate salt of a nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which is manifested depending on the tissue or species. (NCI04) |
|
| Display_Name |
Toremifene Citrate |
|
| FDA_UNII_Code |
2498Y783QT |
|
| FULL_SYN |
2-(p-[(Z)-4-chloro-1,2-diphenyl-1-butenyl]-phenoxy)- N,N-dimethylethylamine citrate (1:1) (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate (1:1) Toremifene citrate Toremifene Citrate TOREMIFENE CITRATE Acapodene FC-1157a Fareston GTx-006 |
|
| Has_Free_Acid_Or_Base_Form | ||
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Toremifene Citrate |
|
| Legacy Concept Name |
Toremifene_Citrate |
|
| Maps_To |
Toremifene Citrate |
|
| NCI_Drug_Dictionary_ID |
41103 |
|
| NSC Number |
613680 |
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| PDQ_Closed_Trial_Search_ID |
41103 |
|
| PDQ_Open_Trial_Search_ID |
41103 |
|
| Preferred_Name |
Toremifene Citrate |
|
| prefixIRI |
Thesaurus:C1756 |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0117339 |
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| subClassOf |