loading...| Preferred Name |
Rituximab |
|
| Synonyms |
Rituximab ABBS Rituximab Biosimilar ABP 798 Rituximab Biosimilar SIBP-02 rituximab-abbs PF-05280586 Rituximab-arrx rituximab biosimilar TQB2303 Rituximab-pvvr Rituximab Biosimilar SAIT101 Rituximab ARRX Rituximab Biosimilar PF-05280586 C2B8 Monoclonal Antibody Rituximab PVVR Rituximab Biosimilar CT-P10 Chimeric Anti-CD20 Antibody Rituximab Biosimilar BI 695500 Rituximab Biosimilar IBI301 Monoclonal Antibody IDEC-C2B8 Rituximab Biosimilar GB241 Rituximab-abbs Rituximab Biosimilar RTXM83 IDEC-C2B8 Monoclonal Antibody Rituximab Biosimilar JHL1101 ABP 798 BI 695500 CT-P10 IDEC-102 IDEC-C2B8 Ikgdar MabThera Mabtas RITUXIMAB RTXM83 Riabni Rituxan Rituximab Ruxience Truxima rituximab |
|
| Definitions |
A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1702 |
|
| Accepted_Therapeutic_Use_For |
Diffuse Large B-cell, CD20-positive, Non-Hodgkins Lymphoma (NHL) |
|
| ALT_DEFINITION |
A drug used to treat certain types of B-cell non-Hodgkin lymphoma. It is also used with other drugs to treat chronic lymphocytic leukemia and rheumatoid arthritis. It is being studied in the treatment of other types of cancer and other conditions. Rituximab binds to a protein called CD20, which is found on B-cells, and may kill cancer cells. It is a type of monoclonal antibody. |
|
| CAS_Registry |
174722-31-7 |
|
| CHEBI_ID |
CHEBI:64357 |
|
| code |
C1702 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157711 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C157712 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C128784 |
|
| Contributing_Source |
CTRP FDA GDC HemOnc |
|
| DEFINITION |
A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. (NCI04) |
|
| Display_Name |
Rituximab |
|
| FDA_UNII_Code |
4F4X42SYQ6 |
|
| FULL_SYN |
Rituximab ABBS Rituximab Biosimilar ABP 798 Rituximab Biosimilar SIBP-02 rituximab-abbs PF-05280586 Rituximab-arrx rituximab biosimilar TQB2303 Rituximab-pvvr Rituximab Biosimilar SAIT101 Rituximab ARRX Rituximab Biosimilar PF-05280586 C2B8 Monoclonal Antibody Rituximab PVVR Rituximab Biosimilar CT-P10 Chimeric Anti-CD20 Antibody Rituximab Biosimilar BI 695500 Rituximab Biosimilar IBI301 Monoclonal Antibody IDEC-C2B8 Rituximab Biosimilar GB241 Rituximab-abbs Rituximab Biosimilar RTXM83 IDEC-C2B8 Monoclonal Antibody Rituximab Biosimilar JHL1101 ABP 798 BI 695500 CT-P10 IDEC-102 IDEC-C2B8 Ikgdar MabThera Mabtas RITUXIMAB RTXM83 Riabni Rituxan Rituximab Ruxience Truxima rituximab |
|
| Has_Target | ||
| Is_Value_For_GDC_Property | ||
| label |
Rituximab |
|
| Legacy Concept Name |
Rituximab |
|
| Maps_To |
Rituximab |
|
| NCI_Drug_Dictionary_ID |
42613 |
|
| NSC Number |
687451 |
|
| PDQ_Closed_Trial_Search_ID |
42613 |
|
| PDQ_Open_Trial_Search_ID |
42613 |
|
| Preferred_Name |
Rituximab |
|
| prefixIRI |
Thesaurus:C1702 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance Immunologic Factor |
|
| UMLS_CUI |
C0393022 |
|
| subClassOf |