loading...| Preferred Name |
Recombinant Human Stem Cell Factor |
|
| Synonyms |
c-Kit Ligand Recombinant Human Stem Cell Factor Steel Factor Mast Cell Growth Factor |
|
| Definitions |
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1410 |
|
| code |
C1410 |
|
| Concept_In_Subset | ||
| DEFINITION |
A therapeutic glycoprotein cytokine chemically identical to or similar to endogenous human stem cell factor with hematopoietic activity. Recombinant human stem cell factor (rhSCF) binds to the receptor tyrosine kinase c-kit, which may stimulate the growth of peripheral blood progenitor cells (PBPCs). This agent works synergistically with other hematopoietic growth factors. rhSCF may promote bone marrow recovery after myeloablative therapies and procedures. |
|
| FULL_SYN |
c-Kit Ligand Recombinant Human Stem Cell Factor Steel Factor Mast Cell Growth Factor |
|
| label |
Recombinant Human Stem Cell Factor |
|
| Legacy Concept Name |
Therapeutic_Stem_Cell_Factor |
|
| NCI_Drug_Dictionary_ID |
41929 |
|
| PDQ_Closed_Trial_Search_ID |
41929 |
|
| PDQ_Open_Trial_Search_ID |
41929 |
|
| Preferred_Name |
Recombinant Human Stem Cell Factor |
|
| prefixIRI |
Thesaurus:C1410 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
|
| UMLS_CUI |
C1526982 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.obolibrary.org/obo/NCIT_C1410 | BERO | LOOM | |
| http://purl.bioontology.org/ontology/PDQ/CDR0000041929 | PDQ | LOOM |