National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Leukotriene E4

Synonyms

Leukotriene E(4)

(5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-6-((2-Amino-2-Carboxyethyl)Thio)-5-Hydroxy-7,9,11,14-Eicosatetraenoic Acid

(7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-Hydroxyicosa-7,9,11,14-Tetraenoate

S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-Hydroxybutyl]Pentadeca-2,4,6,9-Tetraen-1-yl}-L-Cysteine

7,9,11,14-Eicosatetraenoic Acid, 6-((2-Amino-2-Carboxyethyl)Thio)-5-Hydroxy-, (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-

5S-Hydroxy,6R-(S-Cysteinyl),7E,9E,11Z,14Z-Eicosatetraenoic Acid

Leukotriene E4

LEUKOTRIENE E4

(5S,6R,7E,9E,11Z,14Z)-6-(2-Amino-2-Carboxyethyl)Sulfanyl-5-Hydroxyicosa-7,9,11,14-Tetraenoic Acid

(7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-Hydroxyeicosa-7,9,11,14-Tetraenoate

LTE4

Definitions

The final and most stable product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, with inflammatory activity. Because of its inherent stability, leukotriene E4 is used as a marker for leukotriene production.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C129009

CAS_Registry

75715-89-8

CHEBI_ID

CHEBI:15650

Chemical_Formula

C23H37NO5S

code

C129009

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

The final and most stable product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, with inflammatory activity. Because of its inherent stability, leukotriene E4 is used as a marker for leukotriene production.

Display_Name

Leukotriene E4

FDA_UNII_Code

8EYT8ATL7G

FULL_SYN

Leukotriene E(4)

(5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-6-((2-Amino-2-Carboxyethyl)Thio)-5-Hydroxy-7,9,11,14-Eicosatetraenoic Acid

(7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-Hydroxyicosa-7,9,11,14-Tetraenoate

S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-Hydroxybutyl]Pentadeca-2,4,6,9-Tetraen-1-yl}-L-Cysteine

7,9,11,14-Eicosatetraenoic Acid, 6-((2-Amino-2-Carboxyethyl)Thio)-5-Hydroxy-, (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-

5S-Hydroxy,6R-(S-Cysteinyl),7E,9E,11Z,14Z-Eicosatetraenoic Acid

Leukotriene E4

LEUKOTRIENE E4

(5S,6R,7E,9E,11Z,14Z)-6-(2-Amino-2-Carboxyethyl)Sulfanyl-5-Hydroxyicosa-7,9,11,14-Tetraenoic Acid

(7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-Hydroxyeicosa-7,9,11,14-Tetraenoate

LTE4

label

Leukotriene E4

Preferred_Name

Leukotriene E4

prefixIRI

Thesaurus:C129009

Semantic_Type

Organic Chemical

UMLS_CUI

C0125644

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C608

Delete Subject Author Type Created
No notes to display