National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Recombinant Granulocyte Colony-Stimulating Factor
Synonyms

Recombinant Colony-Stimulating Factor 3

Recombinant Granulocyte Colony-Stimulating Factor

rhG-CSF
Definitions

A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04)
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1287
Accepted_Therapeutic_Use_For

Neutropenia
CAS_Registry

143011-72-7
code

C1287
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424
DEFINITION

A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine granulocyte colony-stimulating factor (G-CSF). Secreted by monocytes, macrophages and neutrophils and other cells after activation, G-CSF stimulates the proliferation and differentiation of hematopoietic progenitor cells committed to the neutrophil/ granulocyte lineage. (NCI04)
FULL_SYN

Recombinant Colony-Stimulating Factor 3

Recombinant Granulocyte Colony-Stimulating Factor

rhG-CSF
label

Recombinant Granulocyte Colony-Stimulating Factor
Legacy Concept Name

Recombinant_Granulocyte_Colony_Stimulating_Factor
NCI_Drug_Dictionary_ID

618712
PDQ_Closed_Trial_Search_ID

618712
PDQ_Open_Trial_Search_ID

618712
Preferred_Name

Recombinant Granulocyte Colony-Stimulating Factor
prefixIRI

Thesaurus:C1287
Semantic_Type

Amino Acid, Peptide, or Protein

Immunologic Factor
UMLS_CUI

C0376562
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C387
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