National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
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Preferred Name

Platinum-Group Metal
Synonyms

Platinum Family

Platinum-Group Element

Platinum-Group Metal

Platinum Group

Platinum Metal

PGE

PGM

Platidise

Platinide

Platinoid
Definitions

Six transition metals (iridium, osmium, palladium, platinum, rhodium, and ruthenium) clustered in the d-block of the periodic table (groups 8, 9, and 10, periods 5 and 6) with potential antibiotic and chemotherapeutic activities. Administration of agents containing platinum-group metals can produce DNA crosslinks and adducts in rapidly dividing cells, which can lead to bacterial lysis or eukaryotic cell apoptosis. Additionally, these elements are highly resistant to chemical and thermal challenges, which allow these metals to be used in many industrial applications.
ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C113467
code

C113467
Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977
Contributing_Source

CTRP
DEFINITION

Six transition metals (iridium, osmium, palladium, platinum, rhodium, and ruthenium) clustered in the d-block of the periodic table (groups 8, 9, and 10, periods 5 and 6) with potential antibiotic and chemotherapeutic activities. Administration of agents containing platinum-group metals can produce DNA crosslinks and adducts in rapidly dividing cells, which can lead to bacterial lysis or eukaryotic cell apoptosis. Additionally, these elements are highly resistant to chemical and thermal challenges, which allow these metals to be used in many industrial applications.
Display_Name

Platinum-Group Metal
FULL_SYN

Platinum Family

Platinum-Group Element

Platinum-Group Metal

Platinum Group

Platinum Metal

PGE

PGM

Platidise

Platinide

Platinoid
label

Platinum-Group Metal
Preferred_Name

Platinum-Group Metal
prefixIRI

Thesaurus:C113467
Semantic_Type

Inorganic Chemical
UMLS_CUI

C3815181
subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C637
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