loading...| Preferred Name |
Prostaglandin E2 |
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| Synonyms |
5-Heptenoic Acid, 7-(3-Hydroxy-2-(3-Hydroxy-1-Octenyl)-5-Oxocyclopentyl)- (8CI) Prosta-5,13-Dien-1-Oic Acid, (5Z,11-Alpha,13E,15S)-11,15-Dihydroxy-9-Oxo- (5Z,13E,15S)-11alpha,15-Dihydroxy-9-Oxoprosta-5,13-Dien-1-Oic Acid (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-Oxoprost-13-Enoate Prosta-5,13-Dien-1-Oic Acid, 11,15-Dihydroxy-9-Oxo-, (5Z,11alpha,13E,15S)- 7-(3-Hydroxy-2-(3-Hydroxy-1-Octenyl)-5-Oxocyclopentyl)-5-Heptenoic Acid (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-Oxoprosta-5,13-Dien-1-Oic Acid Prostaglandin E(2) (Z)-7-((1R,2R,3R)-3-Hydroxy-2-((S,E)-3-Hydroxyoct-1-Enyl)-5-Oxocyclopentyl)Hept-5-Enoic Acid Prostaglandin E2 (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-Oxoprosta-5,13-Dienoate (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-Hydroxy-1-Octenyl))-5-Oxocyclopentyl)-5-Heptenoic Acid PGE(2) PGE2 |
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| Definitions |
A prostaglandin with 2 double bonds that is generated by the action of prostaglandin E synthases on prostaglandin H2. Prostaglandin E2 is a mediator of active inflammation, and has important biologic effects including potent vasodilation, smooth muscle relaxation, stimulation of osteoclast-dependent bone resorption and induction of both pain and fever. It is also used as a vaginal suppository during labor to soften the cervix and promote uterine contractions. |
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| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C112043 |
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| CAS_Registry |
363-24-6 |
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| CHEBI_ID |
CHEBI:15551 |
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| code |
C112043 |
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| Concept_In_Subset | ||
| Contributing_Source |
CTRP |
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| DEFINITION |
A prostaglandin with 2 double bonds that is generated by the action of prostaglandin E synthases on prostaglandin H2. Prostaglandin E2 is a mediator of active inflammation, and has important biologic effects including potent vasodilation, smooth muscle relaxation, stimulation of osteoclast-dependent bone resorption and induction of both pain and fever. It is also used as a vaginal suppository during labor to soften the cervix and promote uterine contractions. |
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| Display_Name |
Prostaglandin E2 |
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| FULL_SYN |
5-Heptenoic Acid, 7-(3-Hydroxy-2-(3-Hydroxy-1-Octenyl)-5-Oxocyclopentyl)- (8CI) Prosta-5,13-Dien-1-Oic Acid, (5Z,11-Alpha,13E,15S)-11,15-Dihydroxy-9-Oxo- (5Z,13E,15S)-11alpha,15-Dihydroxy-9-Oxoprosta-5,13-Dien-1-Oic Acid (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-Oxoprost-13-Enoate Prosta-5,13-Dien-1-Oic Acid, 11,15-Dihydroxy-9-Oxo-, (5Z,11alpha,13E,15S)- 7-(3-Hydroxy-2-(3-Hydroxy-1-Octenyl)-5-Oxocyclopentyl)-5-Heptenoic Acid (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-Oxoprosta-5,13-Dien-1-Oic Acid Prostaglandin E(2) (Z)-7-((1R,2R,3R)-3-Hydroxy-2-((S,E)-3-Hydroxyoct-1-Enyl)-5-Oxocyclopentyl)Hept-5-Enoic Acid Prostaglandin E2 (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-Oxoprosta-5,13-Dienoate (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-Hydroxy-1-Octenyl))-5-Oxocyclopentyl)-5-Heptenoic Acid PGE(2) PGE2 |
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| label |
Prostaglandin E2 |
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| Preferred_Name |
Prostaglandin E2 |
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| prefixIRI |
Thesaurus:C112043 |
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| Semantic_Type |
Organic Chemical |
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| UMLS_CUI |
C3813211 |
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| subClassOf |