Preferred Name |
Oxcarbazepine |
|
Synonyms |
|
|
ID |
http://scai.fraunhofer.de/MSOntology#Oxcarbazepine |
|
Context |
MESH :C036006 Drug :DBA000769 |
|
isDefinedBy |
A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses. |
|
prefixIRI |
MSOntology:Oxcarbazepine |
|
prefLabel |
Oxcarbazepine |
|
subClassOf |
Create mapping