loading...| Preferred Name |
valdecoxib |
|
| Synonyms |
4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide SC 65872 VALDECOXIB bextra |
|
| Definitions |
A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation. [url:http://purl.obolibrary.org/obo/NCIT_C1869] |
|
| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:03069 |
|
| definition |
A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation. [url:http://purl.obolibrary.org/obo/NCIT_C1869] |
|
| label |
valdecoxib |
|
| MIO_ID |
MIO:03069 |
|
| prefLabel |
valdecoxib |
|
| reference |
NCIT:C1869 |
|
| synonyms |
4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide SC 65872 VALDECOXIB bextra |
|
| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:03044 |