Preferred Name |
fondaparinux |
|
Synonyms |
natural heparin pentasaccharide ORG 31540 PENTA SR 90107 |
|
Definitions |
A synthetic glucopyranoside with antithrombotic activity. Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development. [url:http://purl.obolibrary.org/obo/NCIT_C73142] |
|
ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02151 |
|
definition |
A synthetic glucopyranoside with antithrombotic activity. Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development. [url:http://purl.obolibrary.org/obo/NCIT_C73142] |
|
label |
fondaparinux |
|
MIO_ID |
MIO:02151 |
|
prefLabel |
fondaparinux |
|
reference |
NCIT:C73142 UMLS:C0701492 CHEBI:61033 |
|
synonyms |
natural heparin pentasaccharide ORG 31540 PENTA SR 90107 |
|
subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01096 |