loading...| Preferred Name |
urokinase-type plasminogen activator |
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| Synonyms |
EC 3.4.21.73 urokinase-plasminogen activator U-Plasminogen Activator plasminogen activator, urokinase Urinary Plasminogen Activator Plasminogen Activator, Urinary Urokinase Plasminogen Activator PLAU u-PA uPA urokinase |
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| Definitions |
Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor binding and the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin. An enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory and used to dissolve blood clots or to prevent them from forming. [url:http://purl.obolibrary.org/obo/NCIT_C17242] |
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| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01832 |
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| definition |
Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor binding and the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin. An enzyme that is made in the kidney and found in the urine. A form of this enzyme is made in the laboratory and used to dissolve blood clots or to prevent them from forming. [url:http://purl.obolibrary.org/obo/NCIT_C17242] |
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| label |
urokinase-type plasminogen activator |
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| MIO_ID |
MIO:01832 |
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| prefLabel |
urokinase-type plasminogen activator |
|
| reference |
NCIT:C17242 PMID:33620437 |
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| synonyms |
EC 3.4.21.73 urokinase-plasminogen activator U-Plasminogen Activator plasminogen activator, urokinase Urinary Plasminogen Activator Plasminogen Activator, Urinary Urokinase Plasminogen Activator PLAU u-PA uPA urokinase |
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| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01321 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00716 |