Preferred Name |
Lambert-Eaton myasthenic syndrome |
|
Synonyms |
Eaton-Lambert syndrome |
|
Definitions |
A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. |
|
ID |
http://purl.obolibrary.org/obo/DOID_0050214 |
|
database_cross_reference |
NCI:C3155 UMLS_CUI:C0022972 SNOMEDCT_US_2021_09_01:230688006 MESH:D015624 ICD9CM:358.3 ICD10CM:G70.80 |
|
definition |
A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. |
|
has_exact_synonym |
Eaton-Lambert syndrome Lambert-Eaton syndrome LEMS |
|
has_obo_namespace |
disease_ontology |
|
IAO_0000115 |
A neuromuscular junction disease that is characterized by an abnormality of acetylcholine (ACh) release at the neuromuscular junction which results from an autoimmune attack against voltage-gated calcium channels (VGCC) on the presynaptic motor nerve terminal. |
|
id |
DOID:0050214 |
|
in_subset | ||
label |
Lambert-Eaton myasthenic syndrome |
|
notation |
DOID:0050214 |
|
prefLabel |
Lambert-Eaton myasthenic syndrome |
|
subClassOf |
http://purl.obolibrary.org/obo/DOID_439 |