loading...| Preferred Name |
Clavulanic Acid |
|
| Synonyms |
Clavulanate Potassium 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R-(2alpha,3Z,5alpha)) |
|
| Definitions |
A beta-lactam antibiotic produced by the actinobacterium Streptomyces clavuligerus. It is a suicide inhibitor of bacterial beta-lactamase enzymes. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D019818 |
|
| altLabel |
Clavulanate Potassium Clavulanic Acid, Monosodium Salt Potassium, Clavulanate MM 14151 BRL 14151 MM14151 BRL14151 Clavulanate Clavulanic Acid, Monopotassium Salt Sodium Clavulanate MM-14151 BRL-14151 Potassium Clavulanate Clavulanate, Potassium Clavulanate, Sodium 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R-(2alpha,3Z,5alpha)) |
|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C0137997 C0110038 C0936252 C0055860 C0878527 C0524961 |
|
| DC |
1 |
|
| definition |
A beta-lactam antibiotic produced by the actinobacterium Streptomyces clavuligerus. It is a suicide inhibitor of bacterial beta-lactamase enzymes. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase. |
|
| DX |
19980101 |
|
| EC |
analogs & derivatives:Clavulanic Acids |
|
| HN |
98; use CLAVULANIC ACID (NM) 1980-97 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
Q42OMW3AT8 23521W1S24 85A8F32FMG 0 |
|
| isa | ||
| Machine permutation |
98; CLAVULANIC ACID was indexed under CLAVULANIC ACIDS 1978-97 & LACTAMS 1976-82 |
|
| Mapped from | ||
| MDA |
19970620 |
|
| MMR |
20180629 |
|
| MN |
D03.633.100.300.374.160 D02.065.589.099.374.160 |
|
| notation |
D019818 |
|
| PA |
D065093 |
|
| prefLabel |
Clavulanic Acid |
|
| RR |
Q42OMW3AT8 61177-45-5 (mono-K-salt) 57943-81-4 (mono-Na-salt) 85A8F32FMG 58001-44-8 (Clavulanic Acid) |
|
| TERMUI |
T058966 T359330 T058968 T359329 T058963 T058964 T734909 T058967 T058965 |
|
| TH |
NLM (1999) USP (1998) USAN (1986) FDA SRS (2014) USAN (19XX) INN (19XX) NLM (2010) NLM (1998) USP (19XX) BAN (19XX) |
|
| tui |
T109 T195 |
|
| subClassOf |