A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.
ID
http://purl.bioontology.org/ontology/MESH/D011112
altLabel
Aerosporin
Polymyxin B Sulfate
AQL
AA AD AE AG AI AN BI BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui
C0001714
C0032535
C0699108
DC
1
definition
A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.
DX
19910101
HN
1991(1978); was see under POLYMYXINS 1978-90; was AEROSPORIN see under POLYMYXIN 1971-77, see POLYMYXIN 1963-70; AEROSPORIN was see POLYMYXIN B 1978-93
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