loading...| Preferred Name |
Mechlorethamine |
|
| Synonyms |
Nitrogranulogen |
|
| Definitions |
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D008466 |
|
| altLabel |
Nitrogranulogen NSC10107 Nitrogen Mustard N Oxide Chlormethine Cloramin NSC762 Nitromin N-Oxide, Mechlorethamine Hydrochloride Mitomen N-Oxide, Nitrogen Mustard Nitrogen Mustard N-Oxide NSC-762 Hydrochloride N-Oxide, Mechlorethamine Mechlorethamine N-Oxide Caryolysine NSC 10107 Chlorethazine Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl- Mechlorethamine Hydrochloride N-Oxide Mustine Mechlorethamine Hydrochloride Embichin Hydrochloride, Mechlorethamine Mechlorethamine Oxide NSC-10107 Nitrogen Mustard Mustargen NSC 762 Mechlorethamine N Oxide Methylchlorethamine Bis(2-chloroethyl)methylamine Mechlorethamine Hydrochloride N Oxide |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C0028177 C0701936 C0600265 C0086710 C0917844 C0700294 C0887167 C0600266 C0025034 C0086711 C0007310 C0025033 C0917712 C0917845 |
|
| DC |
1 |
|
| definition |
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. |
|
| DX |
19630101 |
|
| HN |
MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was NITROGEN MUSTARD N-OXIDE (NM) 1984-91 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
50D9XSG0VR 302-70-5 126-85-2 L0MR697HHI 0 |
|
| isa |
http://purl.bioontology.org/ontology/MESH/D018906 http://purl.bioontology.org/ontology/MESH/D007509 |
|
| LT |
TRD |
|
| Machine permutation |
MECHLORETHAMINE OXIDE was heading 1963-79; NITROGEN MUSTARD N-OXIDE was indexed under NITROGEN MUSTARD COMPOUNDS 1984-91 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C507380 http://purl.bioontology.org/ontology/MESH/C056641 http://purl.bioontology.org/ontology/MESH/C066712 http://purl.bioontology.org/ontology/MESH/C042127 http://purl.bioontology.org/ontology/MESH/C074926 http://purl.bioontology.org/ontology/MESH/C035997 http://purl.bioontology.org/ontology/MESH/C037298 http://purl.bioontology.org/ontology/MESH/C044804 http://purl.bioontology.org/ontology/MESH/C500928 http://purl.bioontology.org/ontology/MESH/C052686 http://purl.bioontology.org/ontology/MESH/C052687 http://purl.bioontology.org/ontology/MESH/C037507 http://purl.bioontology.org/ontology/MESH/C037506 http://purl.bioontology.org/ontology/MESH/C093371 http://purl.bioontology.org/ontology/MESH/C026260 http://purl.bioontology.org/ontology/MESH/C042333 |
|
| MDA |
19990101 |
|
| MMR |
20160701 |
|
| MN |
D02.455.526.728.650.529 |
|
| notation |
D008466 |
|
| OL |
use MECHLORETHAMINE to search MECHLORETHAMINE OXIDE 1966-79; use MECHLORETHAMINE (NM) to search NITROGEN MUSTARD N-OXIDE (NM) 1984-91 |
|
| PA |
D002619 D018906 D000477 D007509 |
|
| prefLabel |
Mechlorethamine |
|
| RR |
302-70-5 (N-oxide, HCl) 126-85-2 (N-oxide) 51-75-2 55-86-7 (HCl) L0MR697HHI |
|
| TERMUI |
T025160 T025163 T025155 T025169 T025170 T025164 T360306 T025168 T025165 T025156 T025153 T025152 T025150 T025162 T025167 T025166 T360305 T025157 T025159 T025151 T025171 |
|
| TH |
US NLM (1999) NLM (1966) CA FDA SRS (2014) NLM (1992) UNK (19XX) USAN (19XX) INN (19XX) FDA SRS (2015) USP (19XX) BAN (19XX) FR |
|
| tui |
T109 T131 T121 |
|
| subClassOf |