loading...| Preferred Name |
Disulfiram |
|
| Synonyms |
Disulfide, Tetraethylthiuram |
|
| Definitions |
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D004221 |
|
| altLabel |
Disulfide, Tetraethylthiuram Teturam Esperal Dicupral Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2 Tetraethylthiuram Disulfide Anticol Antabuse Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl- Alcophobin Antabus Bis(diethylthiocarbamoyl) Disulfide |
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR |
|
| cui |
C1569453 C0591096 C0699199 C0012772 C0699200 C0699196 C0699198 C0699197 |
|
| DC |
1 |
|
| definition |
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase. |
|
| DX |
19660101 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
TR3MLJ1UAI 0 |
|
| isa | ||
| LT |
TRD |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C000726772 http://purl.bioontology.org/ontology/MESH/C000720168 http://purl.bioontology.org/ontology/MESH/C000720167 http://purl.bioontology.org/ontology/MESH/C009827 http://purl.bioontology.org/ontology/MESH/C009822 http://purl.bioontology.org/ontology/MESH/C079652 |
|
| MDA |
19990101 |
|
| MMR |
20160705 |
|
| MN |
D02.886.520.150.175 D02.241.081.251.869.220.250 D02.886.706.200.200 |
|
| notation |
D004221 |
|
| PA |
D065086 D000427 |
|
| prefLabel |
Disulfiram |
|
| RR |
97-77-8 (Disulfiram) |
|
| TERMUI |
T012815 T012819 T612909 T012818 T012817 T012816 T012814 T012820 T012823 T012822 T012821 |
|
| TH |
US NL NLM (1995) FDA SRS (2014) ES UNK (19XX) INN (19XX) DE AU USP (19XX) BAN (19XX) FR IE |
|
| tui |
T109 T121 |
|
| subClassOf |